Isoflavones

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Soy isoflavones and immunity.

The amount of soy products consumed in Japan is much greater than that in Western countries. Recent evidence indicates that soy isoflavones play a beneficial role in obesity, cancer, osteoporosis, and cardiovascular disease. The soybean isoflavone genistein is present at high levels in soy products. Genistein is structurally similar to 17beta-estradiol (E2), and genistein has been suggested to ...

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Pharmacokinetics of Dietary Isoflavones

Dietary isoflavones are reported to have significant influences on human health. The beneficial effects reported include reduced risk of cancers, decreased menopausal symptoms, reduced osteoporosis etc. Most of these benefits have been deduced from epidemiological studies involving soy bean as the source of dietary isoflavones, since soy bean is an important food crop in several parts of the wo...

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Isoflavones promote mitochondrial biogenesis.

Mitochondrial damage is often both the cause and outcome of cell injury resulting from a variety of toxic insults, hypoxia, or trauma. Increasing mitochondrial biogenesis after renal proximal tubular cell (RPTC) injury accelerated the recovery of mitochondrial and cellular functions (Biochem Biophys Res Commun 355:734-739, 2007). However, few pharmacological agents are known to increase mitocho...

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Soy isoflavones and breast cancer.

The soybean and its products have been a staple in the Asian diet for centuries. Although intake of soy remains low in most Western populations, the use of soy isoflavone supplements has become commonplace, and an increasing number of food products contain soy ingredients. This review will present an updated summary of the observational results on soy isoflavones and risk of breast cancer devel...

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Glycation is regulated by isoflavones.

The effect of soy isoflavones on the Maillard reaction (MR) was investigated. Model systems composed of the soy protein glycinin (10 mg mL(-1)) and fructose (40 mg mL(-1)) under basic pH (∼12) conditions were employed for testing the anti-glycative effect of the major antioxidant soy isoflavones (genistin and genistein at 10 μg mL(-1)) and a soy isoflavone-rich extract. The contents of total ph...

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ژورنال

عنوان ژورنال: Molecules

سال: 2019

ISSN: 1420-3049

DOI: 10.3390/molecules24061076